MODEL ADEQUACY IN ASSESSING THE PREDICTIVE PERFORMANCE OF REGRESSION MODELS IN PHARMACEUTICAL PRODUCT OPTIMIZATION: THE BEDAQUILINE SOLID LIPID NANOPARTICLE EXAMPLE

This study aimed to assess the predictive performance of first- and second-order regression models in optimizing bedaquiline (BQ) solid lipid nanoparticle (SLN) formulations.A three-step central composite design and graphical optimization process was employed.A design of experiments method was used to evaluate the impact of BQ, Tween 80 (T80), poly

click here In this paper, we investigate the impact of macroprudential policy measures (bundled together into a macroprudential policy index, MPI) on the non-financial corporate sector credit and household credit growth using a one-step system GMM empirical research method.The goal of our paper is to test whether contractionary macroprudential poli

The emergence and rapid spread of the Coronavirus in the spring of 2020 has fundamentally changed our lives.The most important change has been the attempt to minimise face–to–face contacts everywhere in order to keep the epidemic under control.Public gatherings were banned, shopping malls were closed, and sporting events were also cancelled.As

The outbreak of the COVID-19 pandemic has impacted many professions with short-, medium-, read more and long-term consequences.Hence, this study examined the mediating role of sense of coherence (SOC) and resilience in the relation to COVID-19 stress and teachers’ well-being (TWB).It recruited 836 teachers from Ethiopia’s higher-education insti

Aechmea setigera is an endemic bromeliad from Amazon with ornamental potential.Bromeliads have been propagated by tissue culture.The consistency of the culture medium in vitro multiplication influences the rate of propagation.In this sense, the objective of this study was to evaluate different culture systems with the use of 6-benzylaminopurine (BA